vital alpha testo design that we would see a loss of function gain of function using two different pumps but because oxidative stress that’s imposed by that design mmm-hmm very good I should go over to the Q&A I’ll just remind all of our viewers that they can post their questions here in the question and answer box the first one is from anonymous attendee who says amazing work thank you it’s good start next one says why is a TVP better than ECMO as both of them on Lothal yeah so I think that’s that’s what we were just talking about is the idea that both reduced stroke work through two very different mechanisms but one thing I’ll point out for the for the group is that remember the first paper we published was using left atrial to femoral artery bypass so in fact everything is the same they’re the oxygenator and disorient
vital alpha testo canada so we could do the analysis and the metabolomics aspect of this has really changed my thinking the the tubing the pump takes blood from the left atrium which is already oxygenated and puts it back into the arterial tree now in that case we didn’t need to put an oxygenator into the circuit so our next area of exploration and in that group we saw a reduction in infarct size so now by taking right atrial to thermal artery with an oxygenator it starts to isolate down to potentially not only the hemodynamic effects but this question of oxidative stress and isolating down to the oxygenator I think that’s one major difference mmm very good we have a question from Daniel Johnson which I believe is in Daniel Johnson in Stockholm really enjoyed your presentation thank you in the trans valvular unloading experiments do you also look at the location of the mitochondria were there more my fibrillar or substract level was this altering it’s a great question and so we have started to look at that and we don’t have an a